MRI图像中的脑肿瘤分析是一个重要而挑战性的问题，因为误诊可能导致死亡。脑肿瘤在早期阶段的诊断和评估增加了成功治疗的概率。然而，肿瘤，形状和位置的复杂性和各种使其分割和分类复合物。在这方面，许多研究人员提出了脑肿瘤细分和分类方法。本文使用含有MRI图像增强和肿瘤区检测的框架，呈现了一种同时分段和分类MRI图像中的脑肿瘤的方法。最终，提出了一种基于多任务学习方法的网络。主观和客观结果表明，基于评估指标的分割和分类结果更好或与最先进的。

根据世界卫生组织（世卫组织），癌症是全世界第二次死亡原因，仅对2018年的950万人死亡负责。脑肿瘤计数每四个癌症死亡中的一次。因此，准确和及时诊断脑肿瘤会导致更有效的治疗方法。医生只通过脑手术进行活组织检查操作，并且在诊断肿瘤类型后，考虑治疗计划。基于机器学习算法的自动系统可以允许医生以非侵入性措施诊断脑肿瘤。迄今为止，已经提出了几种图像分类方法以辅助诊断和治疗。对于脑肿瘤分类在这项工作中，我们提供基于深度学习的系统，包含编码器块。这些块作为剩余学习的最大池特征送入。我们的方法展示了通过使用有限的医学图像数据集提高磁共振成像（MRI）图像中的肿瘤分类精度来实现有希望的结果。该模型在数据集中的实验评估由3064 MR图像组成的准确度提出95.98％，这比以前关于此数据库的研究更好。

Simulation-based falsification is a practical testing method to increase confidence that the system will meet safety requirements. Because full-fidelity simulations can be computationally demanding, we investigate the use of simulators with different levels of fidelity. As a first step, we express the overall safety specification in terms of environmental parameters and structure this safety specification as an optimization problem. We propose a multi-fidelity falsification framework using Bayesian optimization, which is able to determine at which level of fidelity we should conduct a safety evaluation in addition to finding possible instances from the environment that cause the system to fail. This method allows us to automatically switch between inexpensive, inaccurate information from a low-fidelity simulator and expensive, accurate information from a high-fidelity simulator in a cost-effective way. Our experiments on various environments in simulation demonstrate that multi-fidelity Bayesian optimization has falsification performance comparable to single-fidelity Bayesian optimization but with much lower cost.

With the growth of editing and sharing images through the internet, the importance of protecting the images' authorship has increased. Robust watermarking is a known approach to maintaining copyright protection. Robustness and imperceptibility are two factors that are tried to be maximized through watermarking. Usually, there is a trade-off between these two parameters. Increasing the robustness would lessen the imperceptibility of the watermarking. This paper proposes an adaptive method that determines the strength of the watermark embedding in different parts of the cover image regarding its texture and brightness. Adaptive embedding increases the robustness while preserving the quality of the watermarked image. Experimental results also show that the proposed method can effectively reconstruct the embedded payload in different kinds of common watermarking attacks. Our proposed method has shown good performance compared to a recent technique.

In this paper, deep-learning-based approaches namely fine-tuning of pretrained convolutional neural networks (VGG16 and VGG19), and end-to-end training of a developed CNN model, have been used in order to classify X-Ray images into four different classes that include COVID-19, normal, opacity and pneumonia cases. A dataset containing more than 20,000 X-ray scans was retrieved from Kaggle and used in this experiment. A two-stage classification approach was implemented to be compared to the one-shot classification approach. Our hypothesis was that a two-stage model will be able to achieve better performance than a one-shot model. Our results show otherwise as VGG16 achieved 95% accuracy using one-shot approach over 5-fold of training. Future work will focus on a more robust implementation of the two-stage classification model Covid-TSC. The main improvement will be allowing data to flow from the output of stage-1 to the input of stage-2, where stage-1 and stage-2 models are VGG16 models fine-tuned on the Covid-19 dataset.

Chromosome analysis is essential for diagnosing genetic disorders. For hematologic malignancies, identification of somatic clonal aberrations by karyotype analysis remains the standard of care. However, karyotyping is costly and time-consuming because of the largely manual process and the expertise required in identifying and annotating aberrations. Efforts to automate karyotype analysis to date fell short in aberration detection. Using a training set of ~10k patient specimens and ~50k karyograms from over 5 years from the Fred Hutchinson Cancer Center, we created a labeled set of images representing individual chromosomes. These individual chromosomes were used to train and assess deep learning models for classifying the 24 human chromosomes and identifying chromosomal aberrations. The top-accuracy models utilized the recently introduced Topological Vision Transformers (TopViTs) with 2-level-block-Toeplitz masking, to incorporate structural inductive bias. TopViT outperformed CNN (Inception) models with >99.3% accuracy for chromosome identification, and exhibited accuracies >99% for aberration detection in most aberrations. Notably, we were able to show high-quality performance even in "few shot" learning scenarios. Incorporating the definition of clonality substantially improved both precision and recall (sensitivity). When applied to "zero shot" scenarios, the model captured aberrations without training, with perfect precision at >50% recall. Together these results show that modern deep learning models can approach expert-level performance for chromosome aberration detection. To our knowledge, this is the first study demonstrating the downstream effectiveness of TopViTs. These results open up exciting opportunities for not only expediting patient results but providing a scalable technology for early screening of low-abundance chromosomal lesions.

Time series anomaly detection has applications in a wide range of research fields and applications, including manufacturing and healthcare. The presence of anomalies can indicate novel or unexpected events, such as production faults, system defects, or heart fluttering, and is therefore of particular interest. The large size and complex patterns of time series have led researchers to develop specialised deep learning models for detecting anomalous patterns. This survey focuses on providing structured and comprehensive state-of-the-art time series anomaly detection models through the use of deep learning. It providing a taxonomy based on the factors that divide anomaly detection models into different categories. Aside from describing the basic anomaly detection technique for each category, the advantages and limitations are also discussed. Furthermore, this study includes examples of deep anomaly detection in time series across various application domains in recent years. It finally summarises open issues in research and challenges faced while adopting deep anomaly detection models.

Bayesian optimization (BO) is increasingly employed in critical applications such as materials design and drug discovery. An increasingly popular strategy in BO is to forgo the sole reliance on high-fidelity data and instead use an ensemble of information sources which provide inexpensive low-fidelity data. The overall premise of this strategy is to reduce the overall sampling costs by querying inexpensive low-fidelity sources whose data are correlated with high-fidelity samples. Here, we propose a multi-fidelity cost-aware BO framework that dramatically outperforms the state-of-the-art technologies in terms of efficiency, consistency, and robustness. We demonstrate the advantages of our framework on analytic and engineering problems and argue that these benefits stem from our two main contributions: (1) we develop a novel acquisition function for multi-fidelity cost-aware BO that safeguards the convergence against the biases of low-fidelity data, and (2) we tailor a newly developed emulator for multi-fidelity BO which enables us to not only simultaneously learn from an ensemble of multi-fidelity datasets, but also identify the severely biased low-fidelity sources that should be excluded from BO.

The BIOSCAN project, led by the International Barcode of Life Consortium, seeks to study changes in biodiversity on a global scale. One component of the project is focused on studying the species interaction and dynamics of all insects. In addition to genetically barcoding insects, over 1.5 million images per year will be collected, each needing taxonomic classification. With the immense volume of incoming images, relying solely on expert taxonomists to label the images would be impossible; however, artificial intelligence and computer vision technology may offer a viable high-throughput solution. Additional tasks including manually weighing individual insects to determine biomass, remain tedious and costly. Here again, computer vision may offer an efficient and compelling alternative. While the use of computer vision methods is appealing for addressing these problems, significant challenges resulting from biological factors present themselves. These challenges are formulated in the context of machine learning in this paper.

In the last few years, various types of machine learning algorithms, such as Support Vector Machine (SVM), Support Vector Regression (SVR), and Non-negative Matrix Factorization (NMF) have been introduced. The kernel approach is an effective method for increasing the classification accuracy of machine learning algorithms. This paper introduces a family of one-parameter kernel functions for improving the accuracy of SVM classification. The proposed kernel function consists of a trigonometric term and differs from all existing kernel functions. We show this function is a positive definite kernel function. Finally, we evaluate the SVM method based on the new trigonometric kernel, the Gaussian kernel, the polynomial kernel, and a convex combination of the new kernel function and the Gaussian kernel function on various types of datasets. Empirical results show that the SVM based on the new trigonometric kernel function and the mixed kernel function achieve the best classification accuracy. Moreover, some numerical results of performing the SVR based on the new trigonometric kernel function and the mixed kernel function are presented.